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NicAlert Cotinine Saliva Strip

NicAlert determines degree of Nicotine smoke exposure by measuring cotinine in saliva. Nicotine, main drug in tobacco smoke, is processed by body into cotinine. (require saliva sample)

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730C/205C vs. Laboratory Testing Test Comparison

Description: This test study was performed on February 1, 2001 using 79 patient samples. Samples were collected at an employment site with aliquots of each forwarded to Forefront Diagnostics and CRL for testing. Samples were tested using the TMS Pack 430C (THC/COC/MOR/MET/PCP/BZO/BAR) test kits. Samples forwarded to CRL for screening/confirmation testing were tested using DRI immunoassay reagents. GC/MS confirmation tests were performed on all samples screening positive by TMS Pack or DRI.

Results: Table 1 shows the final results for all of the TMS Pack tests. Table 2 indicates which samples, screened positive by TMS Pack were confirmed by CRL with their respective GC/MS value (screening values where noted).

Summary: Overall the TMS Pack tests performed extremely well when compared to laboratory testing (immunoassay screening and GC/MS confirmation). An overall accuracy rate of 99% is well within acceptable ranges for screening assays. The study results indicate that users can be confident of the results they obtain using the TMS Pack test kits, when used according to manufacturers directions.

 Table 1

Drug TMS Pack
730C
CRL
(GC/MS)
Accuracy Comments
THC 99%
Positive 13 11 1 - 19ng (screened)
Negative 165 167 1 - Dilute
COCAINE 100%
Positive 4 4
Negative 174 174
MORPHINE 99%
Positive 1 0 Urine Spilled
Negative 178 178
PCP 100%
Positive 0 0
Negative 178 178
METHAMPHETAMINE 99%
Positive 4 3 1 427 (screened)
Negative 174 175
AMPHETAMINE N/A
Positive N/A N/A
Negative N/A N/A
BENZODIAZAPINES 96%
Positive 10 2 5 - ^ cutoff
Negative 168 176
BARBITURATES 100%
Positive 0 0
Negative 178 79
METHADONE N/A
Positive N/A N/A
Negative N/A N/A
Overall Test Accuracy 99%

1.    Note:  Insufficient sample,due to leaking, resulted in several not being tested by CRL.
2.    Note:  CRL did not test for presence of Hydromorphone or Hydrocodone.

Table 2

Positive Results
730C
Confirmed
Y/N
GC/MS Level
(ng/ml)
Comments
THC Y 46
THC Y 57
THC Y 96
THC Y 32
THC Y 87
THC Y 87
THC Y 25
THC Y 148
THC Y 60
THC Y 400
THC N 0 Dilute
THC Y 27
THC Y 399
COC Y 499
COC Y 38485
COC Y 1375
COC Y 2461
MOR Y 0 Spilled Urine
MET Y 30000
MET Y 8163
MET Y 1142
MET Y 427
BZO Y 2000
BZO N 0
BZO N 0
BZO N 295
BZO N 0
BZO N 244
BZO Y 387
BZO N 0
BZO N 286
BZO N 132

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Instructions Articles Guide Results Saliva vs. Urine
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